Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy

Chemotherapy has been reported to upregulate sphingomylinases and increase cellular ceramide, often linked to the induction to cell death. In this work, we show that sublethal doses of doxorubicin and vorinostat still increased cellular ceramide, which was located predominantly at the plasma membran...

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發表在:FASEB J
Main Authors: Canals, Daniel, Salamone, Silvia, Santacreu, Bruno Jaime, Nemeth, Erika, Aguilar, Daniel, Hernandez-Corbacho, María José, Adada, Mohamad, Staquicini, Daniela I., Arap, Wadih, Pasqualini, Renata, Haley, John, Obeid, Lina M, Hannun, Yusuf A
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265206/
https://ncbi.nlm.nih.gov/pubmed/32307766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000205R
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