The doxorubicin-induced cell motility network is under the control of the ceramide activated protein phosphatase 1 alpha

We have recently reported that a specific pool of ceramide, located in the plasma membrane, mediated the effects of sublethal doses of the chemotherapeutic compound doxorubicin on enhancing cancer cell migration. We identified neutral sphingomyelinase 2 (nSMase2) as the enzyme responsible to generat...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Canals, Daniel, Salamone, Silvia, Santacreu, Bruno Jaime, Aguilar, Daniel, Hernandez-Corbacho, María José, Ostermeyer-Fay, Anne G., Greene, Meaghan, Nemeth, Erika, Haley, John D., Obeid, Lina M., Hannun, Yusuf A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220868/
https://ncbi.nlm.nih.gov/pubmed/33583073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202002427R
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