ロード中...

CRISPR editing of the GLI1 first intron abrogates GLI1 expression and differentially alters lineage commitment

GLI1 is one of three GLI family transcription factors that mediate Sonic Hedgehog signaling, which plays a role in development and cell differentiation. GLI1 forms a positive feedback loop with GLI2 and likely with itself. To determine the impact of GLI1 and its intronic regulatory locus on this tra...

詳細記述

保存先:
書誌詳細
出版年:Stem Cells
主要な著者: Galat, Yekaterina, Gu, Haigang, Perepitchka, Mariana, Taylor, Robert, Yoon, Joon Won, Glukhova, Xenia A., Li, Xiao‐Nan, Beletsky, Igor P., Walterhouse, David O., Galat, Vasiliy, Iannaccone, Philip M.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248124/
https://ncbi.nlm.nih.gov/pubmed/33497498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3341
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!