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iPSC-derived progenitor stromal cells provide new insights into aberrant musculoskeletal development and resistance to cancer in down syndrome

Down syndrome (DS) is a congenital disorder caused by trisomy 21 (T21). It is associated with cognitive impairment, muscle hypotonia, heart defects, and other clinical anomalies. At the same time, individuals with Down syndrome have lower prevalence of solid tumor formation. To gain new insights int...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Galat, Yekaterina, Perepitchka, Mariana, Elcheva, Irina, Iannaccone, Stephen, Iannaccone, Philip M., Galat, Vasiliy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414019/
https://ncbi.nlm.nih.gov/pubmed/32764607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69418-9
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