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Aberrant iPSC-derived human astrocytes in Alzheimer's disease

The pathological potential of human astroglia in Alzheimer's disease (AD) was analysed in vitro using induced pluripotent stem cell (iPSC) technology. Here, we report development of a human iPSC-derived astrocyte model created from healthy individuals and patients with either early-onset famili...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Jones, V C, Atkinson-Dell, R, Verkhratsky, A, Mohamet, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386580/
https://ncbi.nlm.nih.gov/pubmed/28333144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.89
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