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iPSC-derived progenitor stromal cells provide new insights into aberrant musculoskeletal development and resistance to cancer in down syndrome

Down syndrome (DS) is a congenital disorder caused by trisomy 21 (T21). It is associated with cognitive impairment, muscle hypotonia, heart defects, and other clinical anomalies. At the same time, individuals with Down syndrome have lower prevalence of solid tumor formation. To gain new insights int...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Galat, Yekaterina, Perepitchka, Mariana, Elcheva, Irina, Iannaccone, Stephen, Iannaccone, Philip M., Galat, Vasiliy
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7414019/
https://ncbi.nlm.nih.gov/pubmed/32764607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69418-9
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