Down syndrome iPSC model: endothelial perspective on tumor development

Trisomy 21 (T21), known as Down syndrome (DS), is a widely studied chromosomal abnormality. Previous studies have shown that DS individuals have a unique cancer profile. While exhibiting low solid tumor prevalence, DS patients are at risk for hematologic cancers, such as acute megakaryocytic leukemi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Perepitchka, Mariana, Galat, Yekaterina, Beletsky, Igor P., Iannaccone, Philip M., Galat, Vasiliy
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486695/
https://ncbi.nlm.nih.gov/pubmed/32934781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27712
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