Dysfunction of iPSC-derived endothelial cells in human Hutchinson–Gilford progeria syndrome

Children with Hutchinson–Gilford progeria syndrome (HGPS) succumb to myocardial infarction and stroke in their teen years. Endothelial dysfunction is an early event in more common forms of atherosclerosis. Endothelial pathobiology may contribute to HGPS, but a comprehensive characterization of endot...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Matrone, Gianfranco, Thandavarayan, Rajarajan A, Walther, Brandon K, Meng, Shu, Mojiri, Anahita, Cooke, John P
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738911/
https://ncbi.nlm.nih.gov/pubmed/31411525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1651587
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