MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells

The role of microRNAs (miRNAs) during mouse early development, especially in endoderm germ layer formation, is largely unknown. Here, via miRNA profiling during endoderm differentiation, we discovered that miR‐124a negatively regulates endoderm lineage commitment in mouse embryonic stem cells (mESCs...

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Bibliografiska uppgifter
I publikationen:Stem Cells
Huvudupphovsmän: Liew, Lee Chuen, Gailhouste, Luc, Tan, Geok Chin, Yamamoto, Yusuke, Takeshita, Fumitaka, Nakagama, Hitoshi, Ochiya, Takahiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Inc. 2019
Ämnen:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187259/
https://ncbi.nlm.nih.gov/pubmed/31828873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3136
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