MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells

The role of microRNAs (miRNAs) during mouse early development, especially in endoderm germ layer formation, is largely unknown. Here, via miRNA profiling during endoderm differentiation, we discovered that miR‐124a negatively regulates endoderm lineage commitment in mouse embryonic stem cells (mESCs...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Liew, Lee Chuen, Gailhouste, Luc, Tan, Geok Chin, Yamamoto, Yusuke, Takeshita, Fumitaka, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187259/
https://ncbi.nlm.nih.gov/pubmed/31828873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3136
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