MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells

The role of microRNAs (miRNAs) during mouse early development, especially in endoderm germ layer formation, is largely unknown. Here, via miRNA profiling during endoderm differentiation, we discovered that miR‐124a negatively regulates endoderm lineage commitment in mouse embryonic stem cells (mESCs...

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Publicat a:Stem Cells
Autors principals: Liew, Lee Chuen, Gailhouste, Luc, Tan, Geok Chin, Yamamoto, Yusuke, Takeshita, Fumitaka, Nakagama, Hitoshi, Ochiya, Takahiro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2019
Matèries:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187259/
https://ncbi.nlm.nih.gov/pubmed/31828873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3136
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