MicroRNA‐124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells

The role of microRNAs (miRNAs) during mouse early development, especially in endoderm germ layer formation, is largely unknown. Here, via miRNA profiling during endoderm differentiation, we discovered that miR‐124a negatively regulates endoderm lineage commitment in mouse embryonic stem cells (mESCs...

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Bibliografske podrobnosti
izdano v:Stem Cells
Main Authors: Liew, Lee Chuen, Gailhouste, Luc, Tan, Geok Chin, Yamamoto, Yusuke, Takeshita, Fumitaka, Nakagama, Hitoshi, Ochiya, Takahiro
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2019
Teme:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187259/
https://ncbi.nlm.nih.gov/pubmed/31828873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3136
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