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Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells

Curative management of pancreatic adenocarcinoma is limited because this malignancy remains resistant to most chemotherapeutic drugs. Strategies that reverse epigenetic alterations offer a unique opportunity for cancer cell reprogramming, which is valuable for development of new treatments. The aim...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gailhouste, Luc, Liew, Lee Chuen, Hatada, Izuho, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920091/
https://ncbi.nlm.nih.gov/pubmed/29700299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0487-z
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