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Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells

Primary liver tumors are mainly represented by hepatocellular carcinoma (HCC), one of the most aggressive and resistant forms of cancer. Liver tumorigenesis is characterized by an accumulation of epigenetic abnormalities, leading to gene extinction and loss of hepatocyte differentiation. The aim of...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hatada, Izuho, Tanaka, Yasuhito, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035736/
https://ncbi.nlm.nih.gov/pubmed/29759938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.04.018
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