Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

Generation of mesencephalic dopamine (mesDA) neurons from human embryonic stem cells (hESCs) requires several stages of signaling from various extrinsic and intrinsic factors. To date, most methods incorporate exogenous treatment of Sonic hedgehog (SHH) to derive mesDA neurons. However, we and other...

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Détails bibliographiques
Auteurs principaux: Denham, Mark, Thompson, Lachlan H, Leung, Jessie, Pébay, Alice, Björklund, Anders, Dottori, Mirella
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2010
Sujets:
Embryonic Stem Cells/induced Pluripotent Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996857/
https://ncbi.nlm.nih.gov/pubmed/20799336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.510
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