Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

Generation of mesencephalic dopamine (mesDA) neurons from human embryonic stem cells (hESCs) requires several stages of signaling from various extrinsic and intrinsic factors. To date, most methods incorporate exogenous treatment of Sonic hedgehog (SHH) to derive mesDA neurons. However, we and other...

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Detalhes bibliográficos
Main Authors: Denham, Mark, Thompson, Lachlan H, Leung, Jessie, Pébay, Alice, Björklund, Anders, Dottori, Mirella
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Embryonic Stem Cells/induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996857/
https://ncbi.nlm.nih.gov/pubmed/20799336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.510
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