Developing stem cell-based therapies for neural repair

Por Parish, Clare L., Thompson, Lachlan H.
Publicado em 2013

Generation of striatal projection neurons extends into the neonatal period in the rat brain

Por Wright, Jordan, Stanic, Davor, Thompson, Lachlan H
Publicado em 2013

Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice

Por Kauhausen, Jessica, Thompson, Lachlan H, Parish, Clare L
Publicado em 2013

Novel pluripotent stem cell lines for enriched grafting in Parkinson’s disease

Por Cota-Coronado, Agustin, Thompson, Lachlan H., Diaz-Martinez, N. Emmanuel
Publicado no Neural Regen Res (2019)

An Optimized Protocol for the Generation of Midbrain Dopamine Neurons under Defined Conditions

Por Gantner, Carlos W., Cota-Coronado, Agustín, Thompson, Lachlan H., Parish, Clare L.
Publicado no STAR Protoc (2020)

Gli1 Is an Inducing Factor in Generating Floor Plate Progenitor Cells from Human Embryonic Stem Cells

Por Denham, Mark, Thompson, Lachlan H, Leung, Jessie, Pébay, Alice, Björklund, Anders, Dottori, Mirella
Publicado em 2010

The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease

Por Grealish, Shane, Jönsson, Marie E., Li, Meng, Kirik, Deniz, Björklund, Anders, Thompson, Lachlan H.
Publicado em 2010

Glycogen Synthase Kinase 3β and Activin/Nodal Inhibition in Human Embryonic Stem Cells Induces a Pre-Neuroepithelial State That Is Required for Specification to a Floor Plate Cell...

Por Denham, Mark, Bye, Chris, Leung, Jessie, Conley, Brock J, Thompson, Lachlan H, Dottori, Mirella
Publicado em 2012

Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors

Por Bye, Chris R., Jönsson, Marie E., Björklund, Anders, Parish, Clare L., Thompson, Lachlan H.
Publicado no Proc Natl Acad Sci U S A (2015)

Axonal Growth of Midbrain Dopamine Neurons is Modulated by the Cell Adhesion Molecule ALCAM Through Trans-Heterophilic Interactions with L1cam, Chl1, and Semaphorins

Por Bye, Christopher R., Rytova, Valeria, Alsanie, Walaa F., Parish, Clare L., Thompson, Lachlan H.
Publicado no J Neurosci (2019)

Ischemic Injury Does Not Stimulate Striatal Neuron Replacement Even during Periods of Active Striatal Neurogenesis

Por Ermine, Charlotte M., Wright, Jordan L., Stanic, Davor, Parish, Clare L., Thompson, Lachlan H.
Publicado no iScience (2020)

Over-Expression of Meteorin Drives Gliogenesis Following Striatal Injury

Por Wright, Jordan L., Ermine, Charlotte M., Jørgensen, Jesper R., Parish, Clare L., Thompson, Lachlan H.
Publicado no Front Cell Neurosci (2016)

Unprecedented Potential for Neural Drug Discovery Based on Self-Organizing hiPSC Platforms

Por Cota-Coronado, Agustín, Durnall, Jennifer C., Díaz, Néstor Fabián, Thompson, Lachlan H., Díaz-Martínez, N. Emmanuel
Publicado no Molecules (2020)

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

Por Ermine, Charlotte M., Somaa, Fahad, Wang, Ting-Yi, Kagan, Brett J., Parish, Clare L., Thompson, Lachlan H.
Publicado no Front Cell Neurosci (2019)

Differential Dopamine Receptor Occupancy Underlies L-DOPA-Induced Dyskinesia in a Rat Model of Parkinson's Disease

Por Sahin, Gurdal, Thompson, Lachlan H., Lavisse, Sonia, Ozgur, Merve, Rbah-Vidal, Latifa, Dollé, Frédéric, Hantraye, Philippe, Kirik, Deniz
Publicado em 2014

Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation

Por Denham, Mark, Parish, Clare L., Leaw, Bryan, Wright, Jordan, Reid, Christopher A., Petrou, Steven, Dottori, Mirella, Thompson, Lachlan H.
Publicado em 2012

Modelling the dopamine and noradrenergic cell loss that occurs in Parkinson's disease and the impact on hippocampal neurogenesis

Por Ermine, Charlotte M., Wright, Jordan L., Frausin, Stefano, Kauhausen, Jessica A., Parish, Clare L., Stanic, Davor, Thompson, Lachlan H.
Publicado no Hippocampus (2018)

Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain

Por Bye, Christopher R., Penna, Vanessa, de Luzy, Isabelle R., Gantner, Carlos W., Hunt, Cameron P.J., Thompson, Lachlan H., Parish, Clare L.
Publicado no Stem Cell Reports (2019)

Long‐Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived from Human Induced Pluripotent Stem Cells After Intracerebral Transplantation

Por Niclis, Jonathan C., Turner, Christopher, Durnall, Jennifer, McDougal, Stuart, Kauhausen, Jessica A., Leaw, Bryan, Dottori, Mirella, Parish, Clare L., Thompson, Lachlan H.
Publicado no Stem Cells Transl Med (2017)

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

Por Niclis, Jonathan C., Gantner, Carlos W., Hunt, Cameron P.J., Kauhausen, Jessica A., Durnall, Jennifer C., Haynes, John M., Pouton, Colin W., Parish, Clare L., Thompson, Lachlan H.
Publicado no Stem Cell Reports (2017)