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Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency
Ornithine transcarbamylase deficiency (OTCD) is a metabolic and genetic disease caused by dysfunction of the hepatocytic urea cycle. To develop new drugs or therapies for OTCD, it is ideal to use models that are more closely related to human metabolism and pathology. Primary human hepatocytes (HHs)...
Kaydedildi:
| Yayımlandı: | J Inherit Metab Dis |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley & Sons, Inc.
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8247293/ https://ncbi.nlm.nih.gov/pubmed/33336822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12347 |
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