Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency

Ornithine transcarbamylase deficiency (OTCD) is a metabolic and genetic disease caused by dysfunction of the hepatocytic urea cycle. To develop new drugs or therapies for OTCD, it is ideal to use models that are more closely related to human metabolism and pathology. Primary human hepatocytes (HHs)...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Inherit Metab Dis
Main Authors: Sugahara, Go, Yamasaki, Chihiro, Yanagi, Ami, Furukawa, Suzue, Ogawa, Yuko, Fukuda, Akinari, Enosawa, Shin, Umezawa, Akihiro, Ishida, Yuji, Tateno, Chise
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247293/
https://ncbi.nlm.nih.gov/pubmed/33336822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jimd.12347
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados