Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes.
100% of primary human hepatocytes infected with an adenoviral vector carrying beta-galactosidase expressed the exogenous gene. Expression was also achieved in > 40% of adult mouse hepatocytes in vivo. Normal levels of activity were achieved in mouse ornithine transcarbamylase (OTC)-deficient primary...
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| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
1993
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288307/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8376608/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116739 |
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