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Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes.

100% of primary human hepatocytes infected with an adenoviral vector carrying beta-galactosidase expressed the exogenous gene. Expression was also achieved in > 40% of adult mouse hepatocytes in vivo. Normal levels of activity were achieved in mouse ornithine transcarbamylase (OTC)-deficient prim...

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Hlavní autoři: Morsy, M A, Alford, E L, Bett, A, Graham, F L, Caskey, C T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC288307/
https://ncbi.nlm.nih.gov/pubmed/8376608
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