تحميل...
Detection of acute toxicity of aflatoxin B1 to human hepatocytes in vitro and in vivo using chimeric mice with humanized livers
Aflatoxin B1 (AFB1), a mycotoxin, is acutely hepatotoxic to many animals including humans. However, there are marked interspecies differences in sensitivity to AFB1-induced toxicity depending on bioactivation by cytochrome P450s (CYPs). In the present study, we examined the applicability of chimeric...
محفوظ في:
| الحاوية / القاعدة: | PLoS One |
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| المؤلفون الرئيسيون: | , , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2020
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7510964/ https://ncbi.nlm.nih.gov/pubmed/32966316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239540 |
| الوسوم: |
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