Acute HBV infection in humanized chimeric mice has multiphasic viral kinetics

BACKGROUND: Chimeric uPA/SCID mice reconstituted with humanized livers are useful for studying HBV infection in the absence of an adaptive immune response. However, the detailed characterization of HBV infection kinetics necessary to enable in-depth mechanistic studies in this novel in vivo HBV infe...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Ishida, Yuji, Chung, Tje Lin, Imamura, Michio, Hiraga, Nobuhiko, Sen, Suranjana, Yokomichi, Hiroshi, Tateno, Chise, Canini, Laetitia, Perelson, Alan S., Uprichard, Susan L., Dahari, Harel, Chayama, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097938/
https://ncbi.nlm.nih.gov/pubmed/29572897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29891
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