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Establishment of ornithine transcarbamylase deficiency-derived primary human hepatocyte with hepatic functions

A long-term hepatocyte culture maintaining liver-specific functions is very essential for both basic research and the development of bioartificial liver devices in clinical application. However, primary hepatocytes rapidly lose their proliferation and hepatic functions over a few days in culture. Th...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Su, Shan, Di Poto, Cristina, Kroemer, Alexander H, Cui, Wanxing, Roy, Rabindra, Liu, Xuefeng, Ressom, Habtom W
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786762/
https://ncbi.nlm.nih.gov/pubmed/31513782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2019.111621
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