Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosis

INTRODUCTION: Phosphorylated tau (p‐tau) in cerebrospinal fluid (CSF) is an established Alzheimer's disease (AD) biomarker. Novel immunoassays targeting N‐terminal and mid‐region p‐tau181 and p‐tau217 fragments are available, but head‐to‐head comparison in clinical settings is lacking. METHODS:...

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Publicat a:Alzheimers Dement
Autors principals: Karikari, Thomas K., Emeršič, Andreja, Vrillon, Agathe, Lantero‐Rodriguez, Juan, Ashton, Nicholas J., Kramberger, Milica Gregorič, Dumurgier, Julien, Hourregue, Claire, Čučnik, Saša, Brinkmalm, Gunnar, Rot, Uroš, Zetterberg, Henrik, Paquet, Claire, Blennow, Kaj
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246793/
https://ncbi.nlm.nih.gov/pubmed/33252199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12236
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