Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosis

INTRODUCTION: Phosphorylated tau (p‐tau) in cerebrospinal fluid (CSF) is an established Alzheimer's disease (AD) biomarker. Novel immunoassays targeting N‐terminal and mid‐region p‐tau181 and p‐tau217 fragments are available, but head‐to‐head comparison in clinical settings is lacking. METHODS:...

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Publicado no:Alzheimers Dement
Main Authors: Karikari, Thomas K., Emeršič, Andreja, Vrillon, Agathe, Lantero‐Rodriguez, Juan, Ashton, Nicholas J., Kramberger, Milica Gregorič, Dumurgier, Julien, Hourregue, Claire, Čučnik, Saša, Brinkmalm, Gunnar, Rot, Uroš, Zetterberg, Henrik, Paquet, Claire, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246793/
https://ncbi.nlm.nih.gov/pubmed/33252199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12236
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