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Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosis

INTRODUCTION: Phosphorylated tau (p‐tau) in cerebrospinal fluid (CSF) is an established Alzheimer's disease (AD) biomarker. Novel immunoassays targeting N‐terminal and mid‐region p‐tau181 and p‐tau217 fragments are available, but head‐to‐head comparison in clinical settings is lacking. METHODS:...

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發表在:Alzheimers Dement
Main Authors: Karikari, Thomas K., Emeršič, Andreja, Vrillon, Agathe, Lantero‐Rodriguez, Juan, Ashton, Nicholas J., Kramberger, Milica Gregorič, Dumurgier, Julien, Hourregue, Claire, Čučnik, Saša, Brinkmalm, Gunnar, Rot, Uroš, Zetterberg, Henrik, Paquet, Claire, Blennow, Kaj
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246793/
https://ncbi.nlm.nih.gov/pubmed/33252199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12236
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