Plasma p-tau181 accurately predicts Alzheimer’s disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline

The neuropathological confirmation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles (NFT) remains the gold standard for a definitive diagnosis of Alzheimer’s disease (AD). Nowadays, the in vivo diagnosis of AD is greatly aided by both cerebrospinal fluid (CSF) and positron emission tomograp...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Lantero Rodriguez, Juan, Karikari, Thomas K., Suárez-Calvet, Marc, Troakes, Claire, King, Andrew, Emersic, Andreja, Aarsland, Dag, Hye, Abdul, Zetterberg, Henrik, Blennow, Kaj, Ashton, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423866/
https://ncbi.nlm.nih.gov/pubmed/32720099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02195-x
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