Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease

IMPORTANCE: Plasma phosphorylated tau at threonine 181 (p-tau181) has been proposed as an easily accessible biomarker for the detection of Alzheimer disease (AD) pathology, but its ability to monitor disease progression in AD remains unclear. OBJECTIVE: To study the potential of longitudinal plasma...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Moscoso, Alexis, Grothe, Michel J., Ashton, Nicholas J., Karikari, Thomas K., Lantero Rodríguez, Juan, Snellman, Anniina, Suárez-Calvet, Marc, Blennow, Kaj, Zetterberg, Henrik, Schöll, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802009/
https://ncbi.nlm.nih.gov/pubmed/33427873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2020.4986
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