Association between polygenic risk score of Alzheimer’s disease and plasma phosphorylated tau in individuals from the Alzheimer’s Disease Neuroimaging Initiative

BACKGROUND: Recent studies suggest that plasma phosphorylated tau181 (p-tau181) is a highly specific biomarker for Alzheimer’s disease (AD)-related tau pathology. It has great potential for the diagnostic and prognostic evaluation of AD, since it identifies AD with the same accuracy as tau PET and C...

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Vydáno v:Alzheimers Res Ther
Hlavní autoři: Zettergren, Anna, Lord, Jodie, Ashton, Nicholas J., Benedet, Andrea L., Karikari, Thomas K., Lantero Rodriguez, Juan, Snellman, Anniina, Suárez-Calvet, Marc, Proitsi, Petroula, Zetterberg, Henrik, Blennow, Kaj
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792087/
https://ncbi.nlm.nih.gov/pubmed/33419453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00754-8
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