Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosis

INTRODUCTION: Phosphorylated tau (p‐tau) in cerebrospinal fluid (CSF) is an established Alzheimer's disease (AD) biomarker. Novel immunoassays targeting N‐terminal and mid‐region p‐tau181 and p‐tau217 fragments are available, but head‐to‐head comparison in clinical settings is lacking. METHODS:...

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Bibliografske podrobnosti
izdano v:Alzheimers Dement
Main Authors: Karikari, Thomas K., Emeršič, Andreja, Vrillon, Agathe, Lantero‐Rodriguez, Juan, Ashton, Nicholas J., Kramberger, Milica Gregorič, Dumurgier, Julien, Hourregue, Claire, Čučnik, Saša, Brinkmalm, Gunnar, Rot, Uroš, Zetterberg, Henrik, Paquet, Claire, Blennow, Kaj
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246793/
https://ncbi.nlm.nih.gov/pubmed/33252199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12236
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