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iRGD-liposomes enhance tumor delivery and therapeutic efficacy of antisense oligonucleotide drugs against primary prostate cancer and bone metastasis

Nucleotide-based drugs, such as antisense oligonucleotides (ASOs), have unique advantages in treating human diseases as they provide virtually unlimited ability to target any gene. However, their clinical translation faces many challenges, one of which is poor delivery to the target tissue in vivo....

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書目詳細資料
發表在:Adv Funct Mater
Main Authors: Guan, Jibin, Guo, Hong, Tang, Tang, Wang, Yihan, Wei, Yushuang, Seth, Punit, Li, Yingming, Dehm, Scott M, Ruoslahti, Erkki, Pang, Hong-Bo
格式: Artigo
語言:Inglês
出版: 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240484/
https://ncbi.nlm.nih.gov/pubmed/34211360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.202100478
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