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Nanoparticles coated with the tumor-penetrating peptide iRGD reduce experimental breast cancer metastasis in the brain

Metastasis is the main killer in cancer; consequently, there is great interest in novel approaches to prevent and treat metastatic disease. Brain metastases are particularly deadly, as the protection of the blood-brain barrier obstructs the passage of common anticancer drugs. This study used magneti...

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Bibliographic Details
Published in:J Mol Med (Berl)
Main Authors: Hamilton, Amanda M., Aidoudi-Ahmed, Sallouha, Sharma, Shweta, Kotamraju, Venkata R., Foster, Paula J., Sugahara, Kazuki N., Ruoslahti, Erkki, Rutt, Brian K.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807972/
https://ncbi.nlm.nih.gov/pubmed/25869026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-015-1279-x
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