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Access granted: iRGD helps silicasome-encased drugs breach the tumor barrier
In this issue of the JCI, Liu et al. use irinotecan-loaded nanoparticles to treat pancreatic adenocarcinomas in mice. Encapsulating drugs into nanoparticles has distinct advantages: it can improve the pharmacokinetics of the drug, enhance efficacy, and reduce unwanted side effects. A drawback is tha...
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| Published in: | J Clin Invest |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5409784/ https://ncbi.nlm.nih.gov/pubmed/28414298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93955 |
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