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iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes

Polymersomes are versatile nanoscale vesicles that can be used for cytoplasmic delivery of payloads. Recently, we demonstrated that pH-sensitive polymersomes exhibit an intrinsic selectivity towards intraperitoneal tumor lesions. A tumor homing peptide, iRGD, harbors a cryptic C-end Rule (CendR) mot...

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Detaylı Bibliyografya
Yayımlandı:Biomaterials
Asıl Yazarlar: Simón-Gracia, Lorena, Hunt, Hedi, Scodeller, Pablo, Gaitzsch, Jens, Kotamraju, Venkata Ramana, Sugahara, Kazuki N., Tammik, Olav, Ruoslahti, Erkki, Battaglia, Giuseppe, Teesalu, Tambet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5687559/
https://ncbi.nlm.nih.gov/pubmed/27472162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.07.023
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