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Access granted: iRGD helps silicasome-encased drugs breach the tumor barrier

In this issue of the JCI, Liu et al. use irinotecan-loaded nanoparticles to treat pancreatic adenocarcinomas in mice. Encapsulating drugs into nanoparticles has distinct advantages: it can improve the pharmacokinetics of the drug, enhance efficacy, and reduce unwanted side effects. A drawback is tha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
1. Verfasser: Ruoslahti, Erkki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409784/
https://ncbi.nlm.nih.gov/pubmed/28414298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI93955
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