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Telomerase structures and regulation: shedding light on the chromosome end

During genome replication, telomerase adds repeats to the ends of chromosomes to balance the loss of telomeric DNA. The regulation of telomerase activity is of medical relevance, as it has been implicated in human diseases such as cancer, as well as in aging. Until recently, structural information o...

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Detaylı Bibliyografya
Yayımlandı:Curr Opin Struct Biol
Asıl Yazarlar: Nguyen, Thi Hoang Duong, Collins, Kathleen, Nogales, Eva
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240480/
https://ncbi.nlm.nih.gov/pubmed/31202023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.04.009
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