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Telomerase structures and regulation: shedding light on the chromosome end
During genome replication, telomerase adds repeats to the ends of chromosomes to balance the loss of telomeric DNA. The regulation of telomerase activity is of medical relevance, as it has been implicated in human diseases such as cancer, as well as in aging. Until recently, structural information o...
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| Veröffentlicht in: | Curr Opin Struct Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8240480/ https://ncbi.nlm.nih.gov/pubmed/31202023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.04.009 |
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