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Telomerase structures and regulation: shedding light on the chromosome end
During genome replication, telomerase adds repeats to the ends of chromosomes to balance the loss of telomeric DNA. The regulation of telomerase activity is of medical relevance, as it has been implicated in human diseases such as cancer, as well as in aging. Until recently, structural information o...
Enregistré dans:
| Publié dans: | Curr Opin Struct Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8240480/ https://ncbi.nlm.nih.gov/pubmed/31202023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.04.009 |
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