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The biogenesis and regulation of telomerase holoenzymes
Chromosome stability requires a dynamic balance of DNA loss and gain in each terminal tract of telomeric repeats. Repeat addition by a specialized reverse transcriptase, telomerase, has an important role in maintaining this equilibrium. Insights that have been gained into the cellular pathways for b...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915765/ https://ncbi.nlm.nih.gov/pubmed/16829980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm1961 |
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