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The biogenesis and regulation of telomerase holoenzymes

Chromosome stability requires a dynamic balance of DNA loss and gain in each terminal tract of telomeric repeats. Repeat addition by a specialized reverse transcriptase, telomerase, has an important role in maintaining this equilibrium. Insights that have been gained into the cellular pathways for b...

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Detalhes bibliográficos
Autor principal: Collins, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915765/
https://ncbi.nlm.nih.gov/pubmed/16829980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm1961
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