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Purification of Human Telomerase Complexes Identifies Factors Involved in Telomerase Biogenesis and Telomere Length Regulation

The identities and roles of proteins associated with human telomerase remain poorly defined. To gain insight, we undertook an affinity purification of endogenously assembled human telomerase complexes. We show that specific subsets of H/ACA, Sm, and hnRNP proteins associate with active and inactive...

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Detalhes bibliográficos
Main Authors: Fu, Dragony, Collins, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917595/
https://ncbi.nlm.nih.gov/pubmed/18082603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.09.023
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