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A telomerase holoenzyme protein enhances telomerase RNA assembly with telomerase reverse transcriptase

Telomerase maintains the simple sequence repeats at chromosome ends, protecting cells from genomic rearrangement, proliferative senescence and death. The telomerase reverse transcriptase (TERT) and telomerase RNA (TER) alone can assemble into active enzyme in a heterologous cell extract, but the phy...

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Detalhes bibliográficos
Main Authors: Prathapam, Ramadevi, Witkin, Keren L, O’Connor, Catherine M, Collins, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913471/
https://ncbi.nlm.nih.gov/pubmed/15696174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb900
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