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A telomerase holoenzyme protein enhances telomerase RNA assembly with telomerase reverse transcriptase

Telomerase maintains the simple sequence repeats at chromosome ends, protecting cells from genomic rearrangement, proliferative senescence and death. The telomerase reverse transcriptase (TERT) and telomerase RNA (TER) alone can assemble into active enzyme in a heterologous cell extract, but the phy...

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Bibliografische gegevens
Hoofdauteurs: Prathapam, Ramadevi, Witkin, Keren L, O’Connor, Catherine M, Collins, Kathleen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913471/
https://ncbi.nlm.nih.gov/pubmed/15696174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb900
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