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A telomerase holoenzyme protein enhances telomerase RNA assembly with telomerase reverse transcriptase

Telomerase maintains the simple sequence repeats at chromosome ends, protecting cells from genomic rearrangement, proliferative senescence and death. The telomerase reverse transcriptase (TERT) and telomerase RNA (TER) alone can assemble into active enzyme in a heterologous cell extract, but the phy...

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Autors principals: Prathapam, Ramadevi, Witkin, Keren L, O’Connor, Catherine M, Collins, Kathleen
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913471/
https://ncbi.nlm.nih.gov/pubmed/15696174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb900
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