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A telomerase holoenzyme protein enhances telomerase RNA assembly with telomerase reverse transcriptase
Telomerase maintains the simple sequence repeats at chromosome ends, protecting cells from genomic rearrangement, proliferative senescence and death. The telomerase reverse transcriptase (TERT) and telomerase RNA (TER) alone can assemble into active enzyme in a heterologous cell extract, but the phy...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913471/ https://ncbi.nlm.nih.gov/pubmed/15696174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb900 |
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