Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM). We analyzed the transcriptome in 2 mouse models with non-o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vakrou, Styliani, Liu, Yamin, Zhu, Li, Greenland, Gabriela V., Simsek, Bahadir, Hebl, Virginia B., Guan, Yufan, Woldemichael, Kirubel, Talbot, Conover C., Aon, Miguel A., Fukunaga, Ryuya, Abraham, M. Roselle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222321/
https://ncbi.nlm.nih.gov/pubmed/34162896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89451-6
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