Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM). We analyzed the transcriptome in 2 mouse models with non-o...

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Udgivet i:Sci Rep
Main Authors: Vakrou, Styliani, Liu, Yamin, Zhu, Li, Greenland, Gabriela V., Simsek, Bahadir, Hebl, Virginia B., Guan, Yufan, Woldemichael, Kirubel, Talbot, Conover C., Aon, Miguel A., Fukunaga, Ryuya, Abraham, M. Roselle
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222321/
https://ncbi.nlm.nih.gov/pubmed/34162896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89451-6
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