Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models

Hypertrophic cardiomyopathy (HCM) stems from mutations in sarcomeric proteins that elicit distinct biophysical sequelae, which in turn may yield radically different intracellular signaling and molecular pathologic profiles. These signaling events remain largely unaddressed by clinical trials that ha...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Vakrou, Styliani, Fukunaga, Ryuya, Foster, D. Brian, Sorensen, Lars, Liu, Yamin, Guan, Yufan, Woldemichael, Kirubel, Pineda-Reyes, Roberto, Liu, Ting, Tardiff, Jill C., Leinwand, Leslie A., Tocchetti, Carlo G., Abraham, Theodore P., O’Rourke, Brian, Aon, Miguel A., Abraham, M. Roselle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926940/
https://ncbi.nlm.nih.gov/pubmed/29563334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94493
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