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Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM). We analyzed the transcriptome in 2 mouse models with non-o...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Vakrou, Styliani, Liu, Yamin, Zhu, Li, Greenland, Gabriela V., Simsek, Bahadir, Hebl, Virginia B., Guan, Yufan, Woldemichael, Kirubel, Talbot, Conover C., Aon, Miguel A., Fukunaga, Ryuya, Abraham, M. Roselle
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222321/
https://ncbi.nlm.nih.gov/pubmed/34162896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89451-6
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