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Differences in molecular phenotype in mouse and human hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We investigated the molecular basis of the cardiac phenotype in two mouse models at established disease stage (mouse-HCM), and human myectomy tissue (human-HCM). We analyzed the transcriptome in 2 mouse models with non-o...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Vakrou, Styliani, Liu, Yamin, Zhu, Li, Greenland, Gabriela V., Simsek, Bahadir, Hebl, Virginia B., Guan, Yufan, Woldemichael, Kirubel, Talbot, Conover C., Aon, Miguel A., Fukunaga, Ryuya, Abraham, M. Roselle
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222321/
https://ncbi.nlm.nih.gov/pubmed/34162896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89451-6
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