Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling

The interaction of the human FcγRIIA with immune complexes (ICs) promotes neutrophil activation and thus must be tightly controlled to avoid damage to healthy tissue. Here, we demonstrate that a fungal-derived soluble β-1,3/1,6-glucan binds to the glycosphingolipid long-chain lactosylceramide (LacCe...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Okubo, Koshu, Brenner, Michael D., Cullere, Xavier, Saggu, Gurpanna, Patchen, Myra L., Bose, Nandita, Mihori, Saki, Yuan, Zhou, Lowell, Clifford A., Zhu, Cheng, Mayadas, Tanya N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218468/
https://ncbi.nlm.nih.gov/pubmed/34010642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109142
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