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Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling
The interaction of the human FcγRIIA with immune complexes (ICs) promotes neutrophil activation and thus must be tightly controlled to avoid damage to healthy tissue. Here, we demonstrate that a fungal-derived soluble β-1,3/1,6-glucan binds to the glycosphingolipid long-chain lactosylceramide (LacCe...
שמור ב:
| הוצא לאור ב: | Cell Rep |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8218468/ https://ncbi.nlm.nih.gov/pubmed/34010642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109142 |
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