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Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling
The interaction of the human FcγRIIA with immune complexes (ICs) promotes neutrophil activation and thus must be tightly controlled to avoid damage to healthy tissue. Here, we demonstrate that a fungal-derived soluble β-1,3/1,6-glucan binds to the glycosphingolipid long-chain lactosylceramide (LacCe...
में बचाया:
| में प्रकाशित: | Cell Rep |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2021
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8218468/ https://ncbi.nlm.nih.gov/pubmed/34010642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109142 |
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