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Inhibitory affinity modulation of FcγRIIA ligand binding by glycosphingolipids by inside-out signaling
The interaction of the human FcγRIIA with immune complexes (ICs) promotes neutrophil activation and thus must be tightly controlled to avoid damage to healthy tissue. Here, we demonstrate that a fungal-derived soluble β-1,3/1,6-glucan binds to the glycosphingolipid long-chain lactosylceramide (LacCe...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8218468/ https://ncbi.nlm.nih.gov/pubmed/34010642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109142 |
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