Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases

The kidney glomerular capillaries are frequent sites of immune complex deposition and subsequent neutrophil accumulation in post-infectious and rapidly progressive glomerulonephritis. However, the mechanisms of neutrophil recruitment remain enigmatic, and there is no targeted therapeutic to avert th...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Nishi, Hiroshi, Furuhashi, Kazuhiro, Cullere, Xavier, Saggu, Gurpanna, Miller, Mark J., Chen, Yunfeng, Rosetti, Florencia, Hamilton, Samantha L., Yang, Lihua, Pittman, Spencer P., Liao, Jiexi, Herter, Jan M., Berry, Jeffrey C., DeAngelo, Daniel J., Zhu, Cheng, Tsokos, George C., Mayadas, Tanya N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617671/
https://ncbi.nlm.nih.gov/pubmed/28891817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94039
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