PKC‐δ activation in neutrophils promotes fungal clearance

The C‐type lectin receptor dectin‐1 and the integrin Mac‐1 have key roles in controlling fungal infection. Here, we demonstrate that dectin‐1‐ and Mac‐1‐induced activation of protein kinase Cδ in neutrophils, independent of the Card9 adaptor, is required for reactive oxygen species production and fo...

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Библиографические подробности
Опубликовано в: :J Leukoc Biol
Главные авторы: Li, Xun, Cullere, Xavier, Nishi, Hiroshi, Saggu, Gurpanna, Durand, Enrique, Mansour, Michael K., Tam, Jenny M., Song, Xiu‐yu, Lin, Xin, Vyas, Jatin M., Mayadas, Tanya
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Host Defense & Pathophysiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608027/
https://ncbi.nlm.nih.gov/pubmed/26965632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0915-405R
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