PKC‐δ activation in neutrophils promotes fungal clearance

The C‐type lectin receptor dectin‐1 and the integrin Mac‐1 have key roles in controlling fungal infection. Here, we demonstrate that dectin‐1‐ and Mac‐1‐induced activation of protein kinase Cδ in neutrophils, independent of the Card9 adaptor, is required for reactive oxygen species production and fo...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Leukoc Biol
Auteurs principaux: Li, Xun, Cullere, Xavier, Nishi, Hiroshi, Saggu, Gurpanna, Durand, Enrique, Mansour, Michael K., Tam, Jenny M., Song, Xiu‐yu, Lin, Xin, Vyas, Jatin M., Mayadas, Tanya
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Host Defense & Pathophysiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608027/
https://ncbi.nlm.nih.gov/pubmed/26965632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0915-405R
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