Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

Immunotherapies are a promising advance in cancer treatment. However, because only a subset of cancer patients benefits from these treatments it is important to find mechanisms that will broaden the responding patient population. Generally, tumors with high mutational burdens have the potential to e...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lussier, Danielle M., Alspach, Elise, Ward, Jeffrey P., Miceli, Alexander P., Runci, Daniele, White, J. Michael, Mpoy, Cedric, Arthur, Cora D., Kohlmiller, Heather N., Jacks, Tyler, Artyomov, Maxim N., Rogers, Buck E., Schreiber, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214694/
https://ncbi.nlm.nih.gov/pubmed/34099555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2102611118
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