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Tumour neoantigen heterogeneity thresholds provide a time window for combination immunotherapy

Following the advent of cancer immunotherapy, increasing insight has been gained on the role of mutational load and neoantigens as key ingredients in T cell recognition of malignancies. However, not all highly mutational tumours react to immune therapies, and initial success is often followed by eve...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Aguadé-Gorgorió, Guim, Solé, Ricard
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653380/
https://ncbi.nlm.nih.gov/pubmed/33109023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0736
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